When you’re looking for the ultimate homestyle dinner and a way to use up leftover chicken, you can hardly do better than a chicken biscuit casserole. Like other classic comfort foods, this chicken and biscuit bake uses basic ingredients and requires minimal prep time. It combines cooked chicken with vegetables in a creamy, cheesy sauce reminiscent of broccoli cheddar soup. Tender biscuits and a savory topping bake up into a golden brown crust.
This chicken biscuit bake makes enough to feed a big family or to have leftovers for a few days of lunches and dinners. After all, casseroles tend to taste better the next day!
Ingredients for Chicken Biscuit Casserole
- Cooked chicken: Slice the chicken into cubes for this chicken and biscuit casserole. You can use breasts, thighs or a combination of the two.
- Cream of chicken soup: This savory condensed soup is part of the creamy sauce and gives the dish more flavor in general. Use canned or homemade cream of chicken soup.
- Mayonnaise: Use regular, olive oil or avocado oil mayonnaise here. Avoid light or nonfat mayos as they won’t create the right texture in the sauce.
- Cheddar cheese: Sprinkle shredded cheddar cheese into the dish before baking for a bubbly and cheesy chicken and biscuits casserole.
- Buttermilk biscuits: Canned buttermilk biscuits are so convenient here. You can also use frozen biscuits (thaw them first) or your own homemade biscuits.
- Broccoli: Briefly cook the broccoli before chopping and adding it to this dish. Or, pick up some frozen chopped broccoli—thawed and drained, it’ll be tender enough to go straight in.
- Onion: Of all the types of onions, red, yellow or white varieties are fine to use here. Finely dice them for this chicken biscuit bake—you’ll need about 1 cup.
- Eggs: You’ll need two large eggs for the sauce that goes over the biscuits. It’ll make the top of the biscuits crispy and golden.
- Sour cream: Blend sour cream with the eggs to make a sauce to cover the biscuits.
- Worcestershire sauce: Just a little Worcestershire adds a dose of salty, umami flavor to the chicken and biscuit casserole. Worcestershire sauce is meant to enhance the recipe flavors, not overwhelm them. If you’d like a more mild flavor, reduce the amount called for by half.
- Seasonings: Celery seed and salt flavor the topping of this chicken and biscuits casserole.
Directions
Step 1: Combine the casserole ingredients
Preheat the oven to 375°F and have ready a greased 13×9-inch baking dish.
Blend together the cream soup, mayonnaise and Worcestershire sauce in a large bowl. Stir in the cubed chicken, chopped broccoli and diced onion.
Spoon the chicken-sauce mixture into the prepared baking dish, and sprinkle shredded cheddar cheese evenly over the top. Cover the dish and bake it for 20 minutes.
Step 2: Add the biscuits
Separate the canned biscuits and split each one in half. Pull the casserole from the oven. Place the biscuits, cut side down, over the top of the casserole.
Step 3: Top with the sauce and bake
Whisk together the eggs, sour cream, celery seed and salt in a small bowl. Spoon this sauce over the tops of the biscuits.
Put the casserole back in the oven, uncovered, for another 28 to 32 minutes. It’s finished when the biscuits are golden brown and baked.
Recipe Variations
- Add other veggies: Not a fan of broccoli? Substitute other cooked veggies like peas, carrots, diced bell peppers or corn.
- Try a different soup: Other condensed cream soups, like mushroom, celery or cheddar will be equally delicious in this chicken and biscuit casserole.
- Change the spices: If you’re not a fan of celery seed, use other spices in its place, like lemon pepper, curry powder, Italian spice blend, dried parsley, garlic powder or dried thyme.
- Use yogurt instead of sour cream: Substitute an equal amount of plain Greek yogurt for the sour cream in the chicken biscuit bake recipe.
How to Store Chicken Biscuit Casserole
Let the chicken and biscuit bake leftovers cool completely, then tightly cover the dish. It should be stored in the refrigerator.
How long does chicken biscuit casserole last?
When kept refrigerated, chicken and biscuits casserole will last three to four days.
Can you freeze chicken biscuit casserole?
Because it’s made with creamy dairy ingredients, we don’t recommend freezing this chicken and biscuit casserole. Dairy tends to separate and become grainy after freezing, and that would ruin the texture. Instead, plan to eat your chicken biscuit bake within a few days of making it.
How do you reheat chicken biscuit casserole?
Place the covered pan of leftover chicken and biscuit casserole in a 350° oven for 20 to 30 minutes until the casserole is warmed through. You can take the cover off for the last five minutes or so of baking to let the topping crisp up a little.
Chicken Biscuit Casserole Tips
Can you use homemade biscuit dough for chicken biscuit casserole?
From-scratch biscuits are delicious in this chicken and biscuit bake. If you follow these biscuit-making tips, you’ll turn out a flaky dough every time. Roll or pat the biscuit dough to 1/2-inch thickness, then use a cutter to cut out rounds. Place them over the top of the chicken biscuit bake and proceed with the rest of the recipe.
How can you cook chicken for chicken biscuit casserole?
You can cook chicken in several ways for use in recipes like this: in the oven, on the stovetop, or using appliances like a slow cooker or Instant Pot. Our guide to cooking chicken has all these methods and more, so you can find the one that works the best for you. If you don’t want to fuss with cooking chicken yourself, pick up a rotisserie chicken at the store and use the meat in this chicken and biscuit casserole.
What can you serve with chicken biscuit casserole?
When you want to keep things simple, this chicken and biscuit bake has just about everything you need for a complete meal: meat, vegetables and biscuits. If you want to add a side, try a fresh green salad or a cooked veggie like sauteed green beans or roasted cauliflower.
What are some other dinner ideas using leftover chicken?
Leftover chicken can be transformed into dozens of new dinner dishes, from quesadillas to soup to casseroles to salads. Because the chicken is already cooked, you can choose a recipe to fit your schedule—some need just long enough to melt or heat through ingredients, some simmer a little longer to develop flavors. Our collection of leftover chicken recipes will give you enough dinner ideas to last for months.
